Table 5 The top 10 associated targets of 110 drugs with true percentage of associated target before prediction and predicted percentage of association
From: Optimizing drug–target interaction prediction based on random walk on heterogeneous networks
Targets | Percentage of drugs associated with the targets based on DrugBank and ChEMBL (%) | Percentage of drug associations appearing in top-10 target list in our prediction (%) |
|---|---|---|
ADA1A | 7.27 | 60 |
5HT2A | 4.54 | 43.63 |
ADA1B | 7.27 | 35.45 |
5HT1A | 4.54 | 33.63 |
ADRB1 | 5.45 | 31.81 |
5HT1B | 5.45 | 30.90 |
5HT2C | 3.63 | 30 |
ACM2 | 9.09 | 26.36 |
5HT3A | 4.54 | 25.45 |
5HT1D | 5.45 | 23.63 |
ACM3 | 9.09 | 21.81 |
5HT7R | 4.54 | 18.18 |